The aim of this research was to study the effect of the Ficus deltoidea (Mas Cotek) leaves on fasting bloodsugar, renal and lipid profile of Type II diabetic patients. This study was carried out at Polyclinic Balok,located in Kuantan, Pahang, Malaysia. Twenty patients participated in the study and they were divided intotwo (2) groups of ten (10) patients each. The inclusion criteria were registered as diabetic patients in the healthcentre, diagnosed as type II diabetes mellitus for more than one (1) year, age 18 years and above, HbA1c morethan 6.5% and have contactable telephone number. The patients in the intervention group has been given F.deltoidea 350 mg twice daily orally and monitored every 20 days for two (2) months. In conclusion, the effectson fasting blood sugar, HbA1C, renal and lipid profiles were not significant. The patients in the interventiongroup felt energetic and fresh compared to the control.