e-ISSN 2231-8542
ISSN 1511-3701
Hishar, H., R. Price, Fathinul Fikri, A. S., Eddie Lau, W. F., Assunta, C. and A. J. Nordin
Pertanika Journal of Tropical Agricultural Science, Volume 24, Issue 1, January 2016
Keywords: 18F-FLT, 18F-FDG, Positron Emission Tomography (PET), cellular proliferation
Published on: 28 Dec 2015
Development of the positron emission tomography (PET) diagnostic radiopharmaceutical (18F) fluoro-2-deoxy-D-glucose (18F-FDG) subsequently facilitated the discovery and clinical evaluation of several new tracers as imaging markers for cancer. While 18F-FDG is a widely employed marker forenhanced intracellular glycolysis and metabolic function, one of the newer tracers, (18F)-3'-fluoro-3'deoxythymidine (18F-FLT), has been developed as a biomarker for cell proliferation. In this review, the potential of 18F-FLT as a biomarker for cancer imaging is discussed.
ISSN 1511-3701
e-ISSN 2231-8542